AURKB and leukemia: In order to further comprehend the differences in Aurora-A and Aurora-B function, leukemia cell lines C1, SEM, KOPN8 and TIB-202 were each treated with either Aurora A Inhibitor I (1 μM) (Figure 4) or Hesperadin (0.1 μM) (Figure 5) for 2, 4, 6, 12 and 24 hours.