ESR1 and breast cancer: A similar experiment was performed using T47D breast cancer cells and the results obtained (Additional file 2: Figure S2) were very comparable to those obtained in Figure 2A. ChIP experiments performed at the CYP1A1 promoter using AhR and ERα antibodies show that AhR binding increases when cells are co-treated with DIM and ICI 182 780 (Figure 2B), and that ICI 182 780 prevents ERα from being recruited to CYP1A1 (Figure 2C).