In comparison to normal tissue and hyperplasia a significantly (p < 0.05) increased expression of IGF-R1β (Figure 1), GLUT-1 (Figure 2), HK 2 (Figure 3), TKTL1 (Figure 4), LDHA (Figure 5), SDHA (Figure 6), SDHB (Figure 7), and ATP synthase (Figure 8) was observed in cancer cells of OSCC. The gene discussed is LDHA; the disease is cancer.