In comparison to normal tissue and hyperplasia a significantly (p < 0.05) increased expression of IGF-R1β (Figure 1), GLUT-1 (Figure 2), HK 2 (Figure 3), TKTL1 (Figure 4), LDHA (Figure 5), SDHA (Figure 6), SDHB (Figure 7), and ATP synthase (Figure 8) was observed in cancer cells of OSCC. This evidence concerns the gene TKTL1 and cancer.