Moreover, hexanucleotide repeat expansions in C9ORF72 gene, mutations in TAR DNA-binding protein (TARDBP), mutations in the genes for fused in sarcoma (FUS), expanded ataxin 2 (ATXN2) repeats, variants of angiogenin (ANG) and polymorphisms within axon guidance pathway genes might be also linked with ALS (Benkler et al. 2010; He et al. 2013; van Es et al. 2011; Ross et al. 2011; O’Dowd et al. 2012; Duleep and Shefner 2013). This evidence concerns the gene TARDBP and amyotrophic lateral sclerosis.