Given the increasing evidence for an association between Insulin-like Growth Factor (IGF)-I and risk of PCa, the Swedish PCBaSE study evaluated the risk of other IGF-I related cancers (colon, rectum, thyroid, and hematologic cancers) and found an increased risk among those men treated with ADT [8]. The gene discussed is IGF1; the disease is hematopoietic and lymphoid cell neoplasm.