DDIT3 and diffuse large B-cell lymphoma: Since the addition of the monoclonal anti CD20 antibody rituximab significantly improved the outcome (Ramadan et al. 2007; Persky et al. 2008) and PFS of patients with localized DLBCL without leading to a significant increase of toxicity (Pfreundschuh et al. 2011, 2008b), it was administered concomitantely to CHOP in the present case as well.