APOE and Alzheimer disease: However, such a postulate raises the following question: are the recognized genetic risk factors in Caucasians (e.g, monogenic mutations, APOE and GWAS defined-genes) similar of the ones involved in Africans (European Alzheimer's Disease Initiative (EADI) et al. 2013; Cruchaga et al. 2014; Guerreiro et al. 2013)?