PLA2G7 and metabolic syndrome: In a very recent study by Ikonomidis et al. [79] that evaluated 111 angiographically confirmed stable CAD patients, Lp-PLA2 was positively associated with carotid intima-media thickness (CIMT), and in the multivariate analysis Lp-PLA2 was an independent determinant of reactive hyperemia using fingertip peripheral arterial tonometry (RHI-PAT), coronary flow reserve (CFR), CIMT, and pulse wave velocity (PWV) in a model including age, sex, smoking, diabetes, dyslipidemia, and hypertension (P < 0.05 for all vascular markers).