In mice, this may be particularly significant, because there is no known murine homolog for human decoy receptor 3 (DcR-3), which is described as an additional soluble decoy ligand for 3 TNFSF members (TL1A, FasL, and LIGHT) (49), and its level has also been shown to be increased in the serum of patients with RA (34). The gene discussed is TNFRSF6B; the disease is rheumatoid arthritis.