In mice, this may be particularly significant, because there is no known murine homolog for human decoy receptor 3 (DcR-3), which is described as an additional soluble decoy ligand for 3 TNFSF members (TL1A, FasL, and LIGHT) (49), and its level has also been shown to be increased in the serum of patients with RA (34). This evidence concerns the gene TNFSF15 and rheumatoid arthritis.