RAD51 and myalgic encephalomeyelitis/chronic fatigue syndrome: With the discovery that telomeres share many features of CFS, including the appearance of telomeric discontinuities on metaphase chromosomes following exposure to replication stresses (Martinez et al., 2009; Sfeir et al., 2009), as well as sensitivity to ATR (McNees et al., 2010; Pennarun et al., 2010), Rad51 (Badie et al., 2010), and BLM disruption (Sfeir et al., 2009), our chromosome ends can also be considered CFS.