Therefore, ANXA1 mRNA and protein expression in gastric cancer seemed to be fairly congruent: ANXA1 is a differentiation marker.Immortalizated gastric cell, GES1, served as the calibrator and ANXA1 mRNA was down-regulated in 5 of 7 gastric cancer cell lines, whereas up-regulated in HGC-27 and N87 cell lines (Figure 4AF). This evidence concerns the gene ANXA1 and gastric cancer.