In 2011, Moralejo et al. [78] suggested that further elucidating the role of the Gimap5 in T cell survival, development and/or activation would aid in our understanding of the pathways involved in the onset of spontaneous diabetes mellitus type 1 and may ultimately uncover the pathways leading to development of this disease in humans. Here, GIMAP5 is linked to type 1 diabetes mellitus.