Importantly, our results identifying KLF4 as a target of miR-2909 in B-ALL are similar to published reports of miRNA-145-mediated repression of KLF4 in human embryonic stem cells [28] and miR-10b regulation of KLF4 in human esophageal cancer cell lines [29]. The gene discussed is KLF4; the disease is precursor B-cell acute lymphoblastic leukemia.