TH and ischemia: The MI+D rats and D rats expressed a higher percentage of TH-immunoreactive nerve fibers in ischemia border regions than the control rats (Sham: 1.1±0.13%, MI: 5.4±0.42%, D: 3.5±0.32%, MI+D: 8.6±0.54%, p<0.01, Fig4 B and C), indicating that cardiac sympathetic hyperinnervation was induced by 4 weeks of CMS.