This hypothesis also, for the first time, offered an explanation for the so-called “BRCA paradox,” which received its name from the contradictory observations that BRCA1/2 deficient tumor cells very rapidly proliferate, while BRCA1/2-deficient embryos suffer from proliferation defects (and, possibly, therefore succumb to embryo lethality) [5]. This evidence concerns the gene BRCA1 and neoplasm.