On the other hand, the reduced levels of IL-1β and IL-18, and increased levels of IL-16 and MCP-1 in AD CSF did correspond with the postmortem findings in Braak 6 AD brains (Figures 5 and 6), and to some extent (IL-1β and IL-16) postmortem VF. The gene discussed is CCL2; the disease is Alzheimer disease.