Lavery et al. found that Ngal alone is not an effective marker of AKI in VLBW infants due to overall variability in Ngal concentrations among preterm infants in comparison to other populations [9]; however, it was found that infants who did not have other clinical indicators for AKI also tested negative for AKI based on Ngal screening [9]. This evidence concerns the gene LCN2 and acute kidney injury.