The top-scoring function was ‘Connective Tissue Disorders’ (p-values 1.27E-06 to 2.33E-03), which included ‘collagen type XI, alpha 1’, ‘collagen, type XII, alpha 1’, ‘collagen, type V, alpha 2’, ‘fibrillin 1’, ‘interleukin 18 binding protein’, ‘lysyl oxidase-like 2’, ‘matrix metallopeptidase 1 (interstitial collagenase)’, ‘thrombospondin 2’. This evidence concerns the gene PSMA6 and connective tissue disorder.