ITGAX and infection: Interestingly, there was little change in the total size of the CD11c+ MHC-II+ DC compartment after infection (Figure S2A), although its relative composition was altered: in kidneys from uninfected mice, CD11bINT F4/80+ DCs were prominent whilst in infected mice this population decreased in size and a CD11b+ F4/80INT population became more abundant (Figure S2B and S2C).