To date, 11 mutations of MIP have been shown to be associated with congenital cataracts (c.97C>T [p.R33C] [28], c.401A>G [p.E134G] [29], c.413C>G [p.T138R] [29], c.530A>G [p.Y177C] [30], c.559C>T [p.R187C] [31], c.698G>A [p.R233K] [32], c.2 T>C [p.Met1] [33], c.494G>A [p.G165D] [34], IVS-1G>A [p.V203fs] [35], c.638delG [p.G213VfsX46] [36], and c.337C>T [p.R113X] [25]). Here, MIP is linked to early-onset non-syndromic cataract.