CFTR and male infertility: There was no increased risk of male infertility in cases without CFTR variants (p = 0.28), but there was significant risk in cases with either CFTRBD or CFTRCF alleles (p = 0.023; OR 10.7; CI 1.03–536) or as a recessive genotype (p = 1.2×10−7; OR 303; CI 23–15783) (Table 2).