LAMP1 and HIV infectious disease: Notably, there is an inverse relationship between the 12 week PVL change and HCV-specific CD107a surface mobilization on CD8+ T cells (Pearson R = −0.7648, P = 0.01; Figure 3F), suggesting that the capability of HCV-specific CD8+ T-cells to degranulate may represent a correlate of control not unlike what is reported for HIV infection [22].