GNRH1 and breast cancer: The 2005 Oxford Overview (but not the most recent in 2011) included 7,601 women (age of less than 50 years) treated with either OvA (approximately 55%) or ovarian suppression (OvS) with the luteinizing hormone-releasing hormone (LHRH) (that is, goserelin) analogue, confirming a reduction of approximately 30% in recurrence and BC mortality [13].