Our patients were generally at decompensated state because of different causes, therefore the cardiac filling pressures and subsequently the NT-proBNP levels were increased in direct proportion with the degree of decompensation of HF, but not with the degree of left ventricular systolic dysfunction; So the NT-proBNP levels in plasma and urine correlate better with ventricular end diastolic pressures than LVEF, which was not evaluated in our study. Here, NPPB is linked to hydrops fetalis.