NR3C1 and post-traumatic stress disorder: The decreased levels of cortisol, the increased responsiveness of glucocorticoid receptors, and the increased sensitivity of the HPA negative feedback inhibition are associated with the occurrence of PTSD.46 In order to further assess the interaction between stress hormones and PTSD, Yehuda and colleagues measured dopamine, norepinephrine, and epinephrine concentrations in 22 male patients with PTSD (14 inpatients and eight outpatients) and in 16 non-psychiatric normal males.