Attaran also declares significant correlation between IL6 level and global initiative for chronic obstructive lung disease stage, and BODE index (including body mass index, obstruction, dyspnea, and exercise capacity) and FEV1.23,24 It seems that the difference between our findings and those of Pourfarzam are due to the status of the patients (stable or in exacerbation), severity of diseases and the type of diseases (COPD vs. BO).24 This evidence concerns the gene IL6 and chronic obstructive pulmonary disease.