Only recently, Weibel et al. showed that after subcutaneous implantation of PC14PE6 cells malignant effusion concomitant hematoma formation occurs at the tumor site, and, during oncolytic virotherapy using GLV-1h68 and especially its derivative GLV-1h108, which encodes a single chain antibody against VEGF, tumor-associated hematoma disappeared [61]. The gene discussed is VEGFA; the disease is neoplasm.