Our study has indicated that daily oral administration of 2.5 ml/kg of alive multiprobiotic “Symbiter” containing concentrated biomass of 14 probiotic bacteria of Bifidobacterium, Lactobacillus, Lactococcus, Propionibacterium genera to neonatal MSG-treated rats by 2-weeks courses led to significant reduce of total body and VAT weight, together with improvement in insulin sensitivity and prevention of NAFLD development. The gene discussed is INS; the disease is metabolic dysfunction-associated steatotic liver disease.