FcεRIα promoter polymorphisms have been found to be associated with AICU, and a single nucleotide polymorphism (SNP) of FcεRIα has been reported in aspirin-intolerant asthma and is considered to be an important regulator of IgE serum level in allergic subjects [20,21,22]. The gene discussed is FCER1A; the disease is asthma.