In order to understand how PFEC induced apoptosis of tumor cells and inhibited cell proliferation, we detected gene expression of cell growth and anti- and pro-apoptosis genes such as Akt, PI3K, Bcl-2, Bcl-xL, Bax, Bid and cell proliferation gene cyclin D1 and PCNA in cells by quantitative PCR. Here, AKT1 is linked to neoplasm.