CGA and irritable bowel syndrome: Receiver operator curve (ROC) analysis for CgA cell density in the duodenum revealed that the sensitivity and specificity for a cutoff of <200 cells/mm2 were 86% and 95%, respectively, in IBS-total, 93% and 95% in IBS-D, 72% and 95% in IBS-M, and 87% and 95% in IBS-C (Figure 3).