In addition to the BC cocktail, TGFB1 (10 ng/ml) (Batardet al, 2000) and StemRegenin 1 (SR1, 0.75μM) (Boitano et al, 2010) were used asthe negative and positive control for HSC-e expansion, respectively (Fig5B). Here, TGFB1 is linked to breast cancer.