At 3 weeks and 6 weeks after MI, HDAC1 and HDAC2 levels were upregulated in the infarcted LV (scar) (Figure 1B and C).In the non-infarcted myocardium, there was a trend of increase in HDAC1/2 levels in the LV of 3 w CHF (Figure 2A). Here, HDAC2 is linked to congestive heart failure.