CST3 and acute kidney injury: This study had the following aims: (1) to investigate the levels of serum creatinine, cystatin C, and plasma and urine NGAL over time during the early post-burn period; (2) to estimate the diagnostic utility of the cystatin C and plasma and urine NGAL levels for predicting AKI and mortality in patients with major burn injuries; and (3) to determine the relationships between the levels of these biomarkers and the burn sizes and inhalation injuries, which are known prognostic factors for burn injuries.