We investigated possible associations of the three known VDR SNPs rs731236(A/G)(TaqI), rs1544410(C/T)(BsmI) and rs7975232 (A/C)(ApaI) with obesity in a population from Saudi Arabia, a country where obesity is reaching endemic proportions [2]. The gene discussed is VDR; the disease is obesity due to melanocortin 4 receptor deficiency.