CASP3 and Infertility: Figure 3 presents frequency distribution histograms of negative control (Fig. 3A), positive control (Fig. 3B), and one semen of male partners of infertile couples positive for C. trachomatis qPCR (Fig. 3C). Mean percentage of spermatozoa with activated caspase 3 (±SD) was higher in male partners of infertile couples positive for C. trachomatis qPCR than those of uninfected patients (54.5 ±18.1% vs. 20.8±14%) and the difference was statistically significant (p = <0.001) (Table 4).