TNFRSF11A and esophageal squamous cell carcinoma: Likewise, in elder patients (≥63 years old), RANK rs1805034 T>C polymorphism was also associated with a significantly increased risk of ESCC (CC vs. TT, adjusted OR  = 1.84, 95% CI  = 1.02–3.31, p = 0.041) (Table 4).