Our data clearly show that (i) Nestin-expression serves as novel selective marker for newly formed tumor blood vessels during the process of vascular remodeling and (ii) that Nest-GFP(+) MPSCs are directly involved in vascular remodeling processes in terms of vascular stabilization, serving as a local source for pericytes and SMC (14). This evidence concerns the gene IFNG-AS1 and neoplasm.