The BCC cases were characterized by the lowest intensity of MT-3 expression of all the examined groups (IRS 1.30 ± 1.11), being significantly lower in comparison to normal skin epidermis, AK, and SCC (P = 0.009; P < 0.0001 and P < 0.0001, respectively) (Fig. 2). The gene discussed is IARS1; the disease is skin basal cell carcinoma.