Data show that out of different organ type cancers harboring genetic changes in CIP2A the most predominant alterations (mutations and putative copy-number alterations from GISTIC) occurred in lung squamous cell carcinoma in which the Gene Set / Pathway was altered in more than 50% of all cases (Lung Squamous Cell Carcinoma, TCGA, Nature 2012/Tumors with sequencing and aCGH data: (178)/User-defined List/1gene). The gene discussed is CIP2A; the disease is squamous cell lung carcinoma.