Searching for the mechanisms of induction of CIP2A expression in cancer, they identified proximal −27 to −107 promoter region responsible for MEK-dependent stimulation of CIP2A expression (two functional ETS1 sites on the proximal CIP2A promoter) and reported that ETS1 acts as the transcription factor mediating stimulation of CIP2A expression through the EGFR-MEK pathway. The gene discussed is EGFR; the disease is cancer.