Because HMGA2 overexpressed in mice leads to T-ALL development, we decided to check the level of HMGA2 expression in three different subsets of human T-ALL-TAL/LMO, HOXA and TLX using publically available Gene Expression Omnibus database (http://www.ncbi.nlm.nih.gov/geo/). The gene discussed is HMGA2; the disease is acute lymphoblastic leukemia.