HMGA2 and lymphoma: Figure 2b shows two representative examples from the transgenic animals (upper right) and a wild-type counterpart (upper left). To check whether HMGA2 transgenic mice developed NK/T-NK lymphomas, we performed CD3/NK1.1 double staining of transgenic and age-matched wild-type splenic cells. Flow cytometric analysis revealed no significant difference between the CD3+NK1.1+ cell populations in the transgenic and wild-type animals (0.18±0.05%, n=21 versus 0.2±0.06%, n=5, P=0.44) as shown in Figure 2a (bottom).