MEIS1 and neoplasm: To gain insight into the role of Meis1 in the epidermis, we used a tamoxifen-inducible, epithelial-specific Meis1 knockout model in combination with a Meis1-EGFP reporter and cell marker co-localization studies to analyze its functions in both normal epidermal development and in skin carcinogenesis, using a two-stage carcinogenesis mouse model.