In tumor tissues, CD11c+ cell infiltration was significantly increased by administration of SART3/CD40L+GM-CSF gene-loaded polyplex micelles (Fig. 5A, right panel; P<0.05 vs. mock control, n = 4; Fig. 4B), but no infiltration of CD11c+ cells was detected in the GM-CSF transgene group. Here, CD40LG is linked to neoplasm.