IFNL3 and Hepatic fibrosis: When only the baseline parameters were considered (excluding the presence or absence of RVR), the best logistic regression analysis model demonstrated that the baseline characteristics which independently influenced SVR were IL28B genotype CC [Exp(B) 3.30; 95%CI, 1.74–6.25, p<0.001], plasma HCV-RNA levels <600000 IU/ml [Exp(B) 2.56; 95%CI, 1.26–5.20, p = 0.009] and the absence of significant liver fibrosis [Exp(B) 2.15; 95%CI, 1.14–4.05, p = 0.019].