It is possible that the wild type genotype (NN) can metabolize the active components and free radical better, more rapidly and efficiently than the mutant genotypes (ND, DD), so that these noxious components have little time to damage hepatocytes; thus, a person with the mutant genotype is more sensitive to these components—peoples with ND and DD genotype for GSTO2 are more prone to develop hepatic failure. This evidence concerns the gene GSTO2 and liver failure.