The GSTO2 ND (OR=1.61, 95% CI: 1.14–2.27, p=0.007) and DD (OR=1.8, 95% CI: 1.10–2.95, p=0.02) genotypes were associated with an increased risk of developing hepatic failure that led to LT as compared to NN genotype. The gene discussed is GSTO2; the disease is Hepatic failure.