Of the 28 cases of JAK2 V617F-positive B-CLL patients reported in the literature (Table 1) (6–15), the male and female ratio was 1.6:1 (17 males vs. 11 females), the median age of the males was 69 years (range, 55–94 years) and was 74 years (range, 58–82 years) for the females. The gene discussed is JAK2; the disease is B-cell chronic lymphocytic leukemia.