In the stage IIIB–IV tissues, the positive expression rate of PI3K and p-Akt was 58.6 (51/87) and 45.9% (40/87), respectively, which did not differ significantly with regard to the expression in the stage I–IIIA NSCLC tissues (Figs. 2 and 3). The gene discussed is AKT1; the disease is non-small cell lung carcinoma.