The present data indicated that FXYD3 expression in endometrial cancer tissues was not significantly correlated with the patient age, blood pressure, menopause onset, plasma glucose and lipid levels, family history of cancer, myometrial invasion, cervical invasion, lymphatic metastasis, clinical cancer stage, growth pattern and histological type of the endometrial cancer tumor (P>0.05). The gene discussed is FXYD3; the disease is endometrial cancer.