KRAS and colorectal carcinoma: The CRC cell line Caco2, with endogenous BRAF and KRAS wild type, was transfected with either BRAFV600E or KRASG12V in order to establish cell lines stably expressing mutant BRAF (Caco2-BRAFV600E, Figure S1a) or mutant KRAS (Caco2-KRASG12V, Figure S1b).