Sepsis in isolation from either methicillin resistant Staphylococcus aureus pneumonia or peritonitis increase both pro (Bax) and anti (Bcl-xL) apoptotic mediators in the mitochondrial pathway [28], [30], and the ratio of these plays a critical role in determining whether a cell lives or dies. The gene discussed is BAX; the disease is Methicillin-Resistant Staphylococcus Aureus Pneumonia.